SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bc0ff3b12856535cc8948ffd341163c5f2ac1ec3dce1dad4c4b8becdc58b938c' 
  AND token = 'EPOU//uIkcxQ6MapbxawoBuKjkfcR4JNekaayyclR/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}