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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9c9b1c4a5dfe3308f22ff0ab13a68de7e1dcc7be8df86955db3f79715a886c38' 
  AND token = 'mPfYSHcIWNUrEtCPbHaP0vF2ggWzeMNEahO2UYWSwIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}