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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd21620a7024c7c68633f8d8b3ce142f0225c29d5da999e8832899b2b17d88e69' 
  AND token = 'GJxjeLDkJ+/xG+FAtIaAlDgLtfFT1lpF99efFa9ufDo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}