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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a60a75d13bd524fdfb347dd823d85e651eecbd589e1bc0b54a6e9a5afc54e07' 
  AND token = 'E8YM82Vh0eD0I3D4y4fF9WI1+Esox45BT0T7yfo/PFE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}