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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43c586da4ae7626f7c59c543a81c36c6fa352875b96a399d649b0147db05100f' 
  AND token = 'lpRirir+UGRvjEIMzkivJ6ASiN84LEHLagHcbxQd3bo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}