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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2aea3726b7b47b33cf292f3c4f01edbcf995db0d0e806d129909ff3d6c3c409b' 
  AND token = 'sqfAxzzNXLJuTHtNdUx3gb7SDhhZ2g2pU4ooxvLURCs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}