SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1575e5b7e51dd294c790f6dd2eb3194767bce45195dd1c9d8f2faa0320783d81' 
  AND token = 'O+ysfyWBi9RxslgMXsS4PJjNiBB68gYiZfATJHGdmpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}