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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b54cb5e6e62ac17a5be45016d3e105481275a7134100a5d4dc8f0d12c44013f' 
  AND token = 'Kbc6qJJ98D/cL6oXW1KUoMmaEGRdN3WklRwgaUFCEvs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}