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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '387e390953ec0e40e03d830f595f1fcc52ee9bdb1389490b41ccfbf68436e426' 
  AND token = 'NLhw/GhEyV8bcmr1evCabvQFfIW0SIhbq+Cz8P0+ENg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}