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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0943e6fd3b9f2af255fc89fd5f81be1a90849bf5c8b282316c1c35c9fb5cac77' 
  AND token = 'FSvaTOeglnFeh35VZQtDTk8JqMct0+q1ysfT6kvmzMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}