SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a63362e86e3164b5f349ee53bbbea50edae592e42e950729a941e3d9dcee0803' 
  AND token = 'I+xZd7BH4Q06pPQh3ev7is22OhojgS8ylulmsDnPLso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}