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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f54d16f891cc7f1e2bf1d7d2dc6775bbf665fcf94e107219efc9eda68b292c8' 
  AND token = 'QXnKe39yFCYRSFmMYY7PpTXSu5FgiAk1dzv7NR1qNK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}