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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd243ce8a5eb6e6cb7bd33b54dfeedf87a4369c85a453a2ffa4e760b21796710c' 
  AND token = 'Nrz4ilI35QtfSzHTSrm06vcVuInDHIJD94dx3+RHHZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}