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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de3a2e1d998588ed8ae46330cc300d9fea722962ada42f7854c4fe4e1d7d52a2' 
  AND token = 'D1+Le3giUF3jedW2fRIQqSdF1jGrBiC0OeUV6LRztE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}