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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8210339dff7982492464051db701e577aeeed99cb6850c01780ec6c667c01c21' 
  AND token = '754JtiWxLG3HhN/btYpIfVEeDwery8IpMplMqeUrEA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00070

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}