SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ce01bf7c0418db8912a3a83d848c44316b1894ba727aaff1bdeb13bbee42357' 
  AND token = 'B0HhO06Zccb+qzoqW/e5USH/NIrr272Xx2Rxo2dvVmg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}