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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ac1ab1e09106b363e8f54082187bc860838034f096b996631329eb9516b28da' 
  AND token = '+4rRzlSbMV4CxfbZxaF7qPZqncJiUM08LPvQyQWe7W0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}