SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7effd5f35bb59d84821426b9bf9f049627eb6c6fc12cb0e315a8dd46062e869d' 
  AND token = '+ZHAC0m1sXNd+4mmc4UbvpRvVMPbQcYNrpkGsOlY5Lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}