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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4cc05bd1f2de0017d7ad26a7b2c06cd00e5a53a5bf4de47fd50844cbda744389' 
  AND token = 'PShhKEzfuMWf4U0AgmLYrqTuJ/brq03ttZECfLo82ak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}