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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0e69ed6308ab8c993a2d8b2f4af4350ef2ca31dd7bce6fd9f6f48cf2ee9465c' 
  AND token = 'PvEMU+xCeA6pwrvT1eGEm4XVxdy8d2nS01pPe5O1x94=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}