SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'be13af4e4d6d0ba8e93d3c7921dffe34662deda1302a42e9f52f680c421704d1' 
  AND token = 'uC+9P4aQM68/GPw/sWT1xoQS+Vt5FOKb3+9Q07wJBIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}