SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9061f188b9aed32c3c1b6eeec45a32db71cebf35f91f760cf89f67c12569b5ee' 
  AND token = 'EHy2GrzdmwREKD9UNYL4Vm5aLkNmF3VzJbNg29lgm64=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}