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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '262677b054599db1297fc6d50901ac312a8a980dd6d27a1d6fa32a599341d250' 
  AND token = 'UDUafezaqiC/nI7scvJMzqKTozhzAhBe9KDgW0bzRqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}