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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e5f50860bf1e0ae16b3a07bd5b8875a591f9fdf54cb7eb20c2fd5b530d0ff043' 
  AND token = 'JEJKQMYqleuQkQS5DDzvZfSb8elZzP8tzVhnYwsLhtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}