SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1b9447c4da7d50df408da5e7f16016451ccd1f5038f87a3498e441b25717225' 
  AND token = 'tdk7BXzcobH8ezeva2hM9pCFFhKQli1ydW7UuWnvohA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}