SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff8034ace0a3aa4c63d5bb89bfb1f044b9cbeca2ae7842e7820ec2099af391f6' 
  AND token = 'zl1H8wVo2TZeCdZSBtp2NZRJBRnheGaDejcDY8XYpVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}