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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2278da64ce5b67d9e8a7345440fdf7f9b558ca6ff1799f1adf25e421ca7b41bd' 
  AND token = 'QDJkc4NIKqFYQEBsnZ6mwr3J+mf3L6Ep2tJwWxtOILE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}