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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2723532645ceba8636c319f0b35f1eb4e480b528c46cfdfcaac1c53b490f9a0' 
  AND token = '9irS6MtM7tb9CjGoVMhqeya7ZAi6tlRfjAZbMj3mKDw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}