SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f4bd693c52b17f57d4d8ad449ad9363605e9e8557b0853d29dda98816727a01' 
  AND token = 'u5tO6tr3d7zF6zjiqgBQUabiDFn7S/teVJAFDiXUphY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}