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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ddd3f1e7ff991f92aaaad458d68a8092ffe7125eac0557f816b7b5435aa3d5' 
  AND token = 'ffKZNZXeyZstq36jmt02ai9G6Wkk+G0bj4uIn8hCTrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}