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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '152b1cb5986af45c0d85ed3ca0930d9562702a4216888973ccb278be976fa6f0' 
  AND token = 'uOFegZYCK/EBZ/ekOqnld+QhTbiNl0mNrdhYpM0QM6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}