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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7433a2d9a8154070dcfa2250a81f3873eb728e28c3d753aca0e550e0de5cc741' 
  AND token = '1v3523UJeWG2EjxX6ekYRTUb/2QKyXsD6kAdgUhqwnI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}