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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fc543f4cfe7c9e0fd7f9aa249029bf3efba4049afb1be1b61698c5845cb8f68' 
  AND token = 'H1MfRoRDC6XcWlP3Iq/oP/LrsdnFNCPwJoVp/HVRtZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}