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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65d4d9409cfa6f52a488a34848cd4aff89db934e06f657dc59fdf89c6b45b900' 
  AND token = 'PcUTAjVcX/73Cxfnllg6FswzuNYkmyjGU47siR6snR8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}