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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '646c7c36858d0fd7d47d7e985c7791b24b85d3f499a2ec5164ea637b2331cae9' 
  AND token = 'GioEGa40XlAlfCzj26JA+L1ckE2PS8B5u+wvACVVe6U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}