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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33787c9241efb505c55577359758f57c644ed16834e6790a06131a332e47261f' 
  AND token = '2kFV1e2P6ZtCtIy69K0NttExicv3hBrBYY7/FQj0rTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}