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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '978c0d48409e85559e2f10dbfaed4255ef290d6c4e6d1f68c7253bb87644eaee' 
  AND token = 'SGKenKZcsfVNMqnrEw2Lwe+e/IIMtUo1/vj1i9aK6x4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}