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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce2c60b235faba9c6ca329efba21725181c1a70c97550c8bc8e62be2bc2f61b4' 
  AND token = 'MjW13Z3dDnm6RhTjTJj8q47S/BBnsRxIjW5JzQZSGuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}