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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7421e0b87fcccb7adf5f9888001152aae5a6fd880e30a1768a5e3ba32673178' 
  AND token = 'c9DLk7C+Q0gst7Y70CUzr5ZRa5ubd3iI/MrDxrMmio0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}