SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ad461bfff384aaf1f8b7806726ff5df5bece8cfb6fb1795f475108a97dc088c' 
  AND token = 'Y3sK0wgZouQHOcR2KRoSNesTv8Lv96gB1O4XG69qnsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}