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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f65887f0e37fc6f5da0d8615a40edd5b9d04269504edb11aa495f8737b5a749' 
  AND token = 'lTGDAKA1/8KlB533XmzHhEH8aK7pc3katcqt/zzMko0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}