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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e3bf6ebacd2aa1e3734eb3e00ff3c02ef10f619e3761b9d9f24564dee9b0279' 
  AND token = '4t77dD/fpD9+Cw8N4Q4kCf0vLjNU+I+LfxKtYic1S/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}