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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0225bf4b37a6ce31bb1b7c512fb7f26cf643c7bfdde23576b60b228467d9f3a' 
  AND token = 'EtHTTgUvS8c0Mfv0aNAuK3DYSzl3E67g2WlbOl+GZd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}