SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b19f1e1d693f15d02a42dd1972627a56759db1b78dfcd0faf65794ffc746792' 
  AND token = 'knB8hyAWGy9tAbmPZ9F7CHdlUR7g1x62G77cu2X9tsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}