SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c2b4b2b4121ead41d7adcda961773464c99dea684c2ece21a7466cb913afa53' 
  AND token = '8weFVvj/XeBaBYJLeV7i4VzQMC04zzZ9xRtlHJhGpeg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}