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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12236e9ecced9b21e6249034b7521540a30fd4bc3580c855484f1a42defc34c8' 
  AND token = 'g5QXqrdH0E0QsbC0ygV1jKuubaRqkT+48eVNGKrfRNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}