SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85149945646ff687e2af9cf731965a063d2a933f4ed3c6b4e6b9cb02b97b3ab9' 
  AND token = '9MI2BIi0m+l2BXUVEgss1IxdUIsb3DIKVuWyN8xQmBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00083

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}