SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d8c0cff23684fce5da69601081b88f52ca713d0fe450bc44b1fc36537f504e4' 
  AND token = 'AnMbb/WfCeXEJEgQw1kgAy1HIKkqqHF+1xpq4YnwlPY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}