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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '28a370d656a63c4a9285e40c0072d8070df8c4f9cf862c9fa5821b652595fb07' 
  AND token = 'kQ/aGsTwoxuoVZWphRVTjXdjHchssbP2ocj2S8bAlG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}