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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfe10952329e51322935696b8b7c4aab867b6f371e4e34f6398b2ea3d9a37a00' 
  AND token = '5DMI+eUdZitBwWoQ3i1MkYwfFofjN0HBC0SGCGSbOoY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}